Saffron: A Natural Potent Antioxidant as a Promising Anti-Obesity Drug
نویسندگان
چکیده
Obesity is associated with various diseases, particularly diabetes, hypertension, osteoarthritis and heart disease. Research on possibilities of herbal extracts and isolated compounds from natural products for treating obesity has an upward trend. Saffron (Crocus Sativus L. Iridaceae) is a source of plant polyphenols/carotenoids, used as important spice and food colorant in different parts of the world. It has also been used in traditional medicine for treatment of different types of illnesses since ancient times. Many of these medicinal properties of saffron can be attributed to a number of its compounds such as crocetin, crocins and other substances having strong antioxidant and radical scavenger properties against a variety of radical oxygen species and pro-inflammatory cytokines. The aim of this article is to assess the potential role of saffron and its constituents in the regulation of metabolic functions, which can beneficially alter obesity pathophysiology.
منابع مشابه
Anti-obesity and Anorectic Effects of Saffron and its Constituent Crocin in Obese Wistar Rat
Background: Obesity is pandemic worldwide and a strong risk factor for cardio-metabolic disorders. The few approved anti-obesity drugs have poor efficacy and safety profile. Thus, there is an urgent need for new anti-obesity agents. According to the traditional medicine and a clinical trial, saffron may have anorexigenic and anti-obesity effects which need further investigation. Objectives: Ev...
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Background: Saffron (Crocus satious L.) provides a variety of promising preventive and therapeutic effects with non-considerable side effects. Objective: Based on our knowledge, this is the first study that simultaneously has reviewed the effect of saffron extract and its constituents on the factors associated with neuropsychological, cardiovascular, and gastrointestinal tract diseases. Methods...
متن کاملA Review on the Effects of Saffron Extract and its Constituents on Factors Related to Neurologic, Cardiovascular and Gastrointestinal Diseases
Background: Saffron (Crocus satious L.) provides a variety of promising preventive and therapeutic effects with non-considerable side effects. Objective: Based on our knowledge, this is the first study that simultaneously has reviewed the effect of saffron extract and its constituents on the factors associated with neuropsychological, cardiovascular, and gastrointestinal tract diseases. ...
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